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Can Emotional Stress Cause Skin Cancer?

can emotional stress cause skin cancer

Can stress cause skin cancers like melanoma? This is quite a question, isn't it? Especially since a scientific study just took a look at it and came up with a fascinating connection.

Yes, there is a connection between significant emotional stress and an increased risk of developing basal cell carcinoma skin cancer.

But there's more.  We've known for a long time that stress lowers your immune system in general, but now researchers have found that your adult immune response to fighting basal cell skin cancers is even lower if you had a history of parental emotional abuse in childhood; specifically, people who suffered parental emotional childhood abuse have reduced immune response to basal cell carcinomas when they then experience stress as an adult.

Whether a history of abuse zaps your body's immune reserve to stress or it makes current stress and trauma more traumatizing isn't clear. What is clear is that the childhood abuse experience provides added immune suppression to that of adult stress and trauma, and it can show up on your skin and in the dermatologist's office.

mind body skin wellness expert dr cynthia bailey

Given my interest in the mind-body connection, this increases the depth of understanding we need to bring to the care of skin cancer. Over my years of practice, I've observed the connection between emotionally stressful times in a person's life and their skin going through a "spell" of basal cell cancers. Now we have the immune markers and scientific data to explain it.

My big "aha patient" for the stress/immune/basal cell connection was a woman that I have cared for over many years. About 15 or more years ago she was in the middle of a heart-wrenching phase in her life and her skin was popping basal cell carcinomas like popcorn; out of the blue, she started showing up with 3 or 4 basal cell cancers every visit, even in places where the sun hadn't shown for years.

Yes, like many of my patients, she was middle aged with years of California sun exposure, but it was odd.  Plus, this lovely woman's skin made keloid scars so every basal cell was additionally traumatizing by the lack of control that anyone can have over an itchy and lumpy keloid scar. I saw her many times a year for about 5 years.

Then, miraculously, when her life turned around, poof - like magic - the basal cell carcinomas stopped. It’s been years and nary a one since then; in fact, she barely needs me anymore. We’re both thrilled that her skin turned around just as her life did.

I’ll always remember her journey and how her skin suffered at the same time her emotional well-being was pelted by life trauma. I’ve observed many more patients whose "skin cancer spells" parallel "emotionally painful spells" and this article helps us wrap our heads around why.

Here are the fascinating connections between basal cell carcinoma development and stress experience found in this scientific study:

  • Among basal cell cancer patients who experienced a recent severe life event, those who were emotionally maltreated by their mothers or fathers as children were more likely to have poorer immune responses.
  • At the same time, childhood emotional maltreatment was unrelated to basal cell carcinoma immune response among those who had not experienced a stressful life event.
In the study, participants who suffered maternal or paternal emotional maltreatment as children were more likely to have poorer immune responses to their basal cell cancers as indicated by lower levels of the immune response markers:  mRNA for CD25, CD3ε, ICAM-1, and CD68.  According to the synopsis of this article on MedPage Today, the study authors note:
“that stressful events and the negative emotions generated by them, especially early in life, can dysregulate immunity enough to produce clinically significant changes, such as impaired responses to vaccines, slowed wound healing, promotion of inflammation, and dampened markers in both innate and adaptive immune function. They explained further that childhood maltreatment has been associated with elevated inflammation and higher antibody titers to the herpes simplex virus type 1 and to multiple diseases including cancer (and that) the immune system plays a prominent role in BCC tumor appearance and progression.”

There's a really important take-home message here for all of us.....

When life dishes out serious stress, we need to take good care of ourselves because significant stress disrupts our immune system. 

can stress cause melanoma and skin cancer

Instead of just soldiering on, we need to create a strategy of nurturing self-care to help our body get through the situation without adverse health consequences.

Stress reduction self-care is doubly important for people with a history of parental emotional abuse during their childhood. 

As for we dermatologists, the health consequences of stress induced immune dysregulation shows up in our offices. We need to be mindful that our job is much more than a skin-deep pursuit. 

Because of the increased risk of skin cancer, this also means that when you are under stress, your nurturing self-care needs to include taking good care of your skin. 

We know that UV rays from the sun cause immune dysfunction inside your skin, resulting in the growth of skin cancers.  Don't compound stress related immune dysfunction with UV immune dysfunction. 

Instead, sun protect your skin to help reduce the risk of basal cell skin cancers adding to your problems:

  1. Wear a good sun hat and cover as much exposed skin as possible with clothing.
  2. Seek the shade when you can instead of staying out in the direct sun.
    Wear a good mineral zinc oxide sunscreen on all uncovered skin 365 days a year. Sunscreens fortified with vitamins C and E are shown to provide extra benefit in reducing UV induced tumorigenesis. My Sheer Strength Pure Physical Matte Tinted SPF 30 contains these vitamins plus other antioxidants and botanicals that can provide benefit to reducing sun damage. 
    Consider adding a potent antioxidant skin care product for your face and neck skin care routine. The 'head and neck'. I recommend proven green tea polyphenol antioxidants in the Green Tea Antioxidant Skin Therapy.

The hat and the sunscreen I can help with! 

best sun protection hats and sunscreen
Click here to see the sunscreens, hats and other practical sun protection tools that I personally use to destress in nature. Enjoy the sun and tranquility while protecting your skin from UV damage and immune suppression that leads to skin cancer. 


Learn more about my patient-proven and dermatologist-approved sun protection.


Kiecolt-Glaser J, et al "Basal cell carcinoma: stressful life events and the tumor environment" Arch Gen Psychiatry 2012; 69: 618-626.